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SEACing the GAP that nEGOCiates TORC1 activation: Evolutionary conservation of Rag GTPase regulation

The target of rapamycin complex 1 (TORC1) regulates eukaryotic cell growth in response to a variety of input signals. In S. cerevisiae, amino acids activate TORC1 through the Rag guanosine triphosphatase (GTPase) heterodimer composed of Gtr1 and Gtr2 found together with Ego1 and Ego3 in the EGO comp...

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Detalles Bibliográficos
Autores principales: Panchaud, Nicolas, Péli-Gulli, Marie-Pierre, De Virgilio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875668/
https://www.ncbi.nlm.nih.gov/pubmed/23974112
http://dx.doi.org/10.4161/cc.26000