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Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab

The autoimmune process in rheumatoid arthritis depends on activation of immune cells, which utilize intracellular kinases to respond to external stimuli such as cytokines, immune complexes, and antigens. CD4+ T cells comprise a large proportion of the inflammatory cells that invade the synovial tiss...

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Detalles Bibliográficos
Autores principales: Chimenti, Maria Sole, Tucci, Paola, Candi, Eleonora, Perricone, Roberto, Melino, Gerry, Willis, Anne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875677/
https://www.ncbi.nlm.nih.gov/pubmed/23974102
http://dx.doi.org/10.4161/cc.26067