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Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab
The autoimmune process in rheumatoid arthritis depends on activation of immune cells, which utilize intracellular kinases to respond to external stimuli such as cytokines, immune complexes, and antigens. CD4+ T cells comprise a large proportion of the inflammatory cells that invade the synovial tiss...
Autores principales: | Chimenti, Maria Sole, Tucci, Paola, Candi, Eleonora, Perricone, Roberto, Melino, Gerry, Willis, Anne E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875677/ https://www.ncbi.nlm.nih.gov/pubmed/23974102 http://dx.doi.org/10.4161/cc.26067 |
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