Computational methods for detecting copy number variations in cancer genome using next generation sequencing: principles and challenges

Accurate detection of somatic copy number variations (CNVs) is an essential part of cancer genome analysis, and plays an important role in oncotarget identifications. Next generation sequencing (NGS) holds the promise to revolutionize somatic CNV detection. In this review, we provide an overview of...

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Detalles Bibliográficos
Autores principales: Liu, Biao, Morrison, Carl D., Johnson, Candace S., Trump, Donald L., Qin, Maochun, Conroy, Jeffrey C., Wang, Jianmin, Liu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875755/
https://www.ncbi.nlm.nih.gov/pubmed/24240121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875755/
https://www.ncbi.nlm.nih.gov/pubmed/24240121

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