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Computational methods for detecting copy number variations in cancer genome using next generation sequencing: principles and challenges
Accurate detection of somatic copy number variations (CNVs) is an essential part of cancer genome analysis, and plays an important role in oncotarget identifications. Next generation sequencing (NGS) holds the promise to revolutionize somatic CNV detection. In this review, we provide an overview of...
Autores principales: | Liu, Biao, Morrison, Carl D., Johnson, Candace S., Trump, Donald L., Qin, Maochun, Conroy, Jeffrey C., Wang, Jianmin, Liu, Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875755/ https://www.ncbi.nlm.nih.gov/pubmed/24240121 |
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