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Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas

Proteolytic enzymes play important roles during tumor development and progression through their ability to promote cell growth or by facilitating the invasion of surrounding tissues. The human genome contains more than 570 protease-coding genes, many of them forming functional networks, which has fo...

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Detalles Bibliográficos
Autores principales: Fraile, Julia M., Ordóñez, Gonzalo R., Quirós, Pedro M., Astudillo, Aurora, Galván, José A., Colomer, Dolors, López-Otín, Carlos, Freije, José M.P., Puente, Xose S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875759/
https://www.ncbi.nlm.nih.gov/pubmed/24243807