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IL-4 Derived from Non-T Cells Induces Basophil- and IL-3-independent Th2 Immune Responses

How Th2 immunity develops in vivo remains obscure. Basophils have been considered key innate cells producing IL-4, a cytokine essential for Th2 immunity. Increasing evidence suggests that basophils are dispensable for the initiation of Th2 immunity. In this study, we revisited the role of basophils...

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Detalles Bibliográficos
Autores principales: Kim, Sohee, Karasuyama, Hajime, Lopez, Angel F., Ouyang, Wenjun, Li, Xiaoxia, Le Gros, Graham, Min, Booki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875783/
https://www.ncbi.nlm.nih.gov/pubmed/24385943
http://dx.doi.org/10.4110/in.2013.13.6.249