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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
Sequence-specific nucleases like TALENs and the CRISPR/Cas9 system have greatly expanded the genome editing possibilities in model organisms such as zebrafish. Both systems have recently been used to create knock-out alleles with great efficiency, and TALENs have also been successfully employed in k...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875856/ https://www.ncbi.nlm.nih.gov/pubmed/24179142 http://dx.doi.org/10.1101/gr.161638.113 |