Cargando…

Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth

DNA sequence variants influence gene expression and cellular phenotypes. In this study, we focused on natural variation in the gene encoding the histone demethylase, KDM4C, which promotes transcriptional activation by removing the repressive histone mark, H3K9me3, from its target genes. We uncovered...

Descripción completa

Detalles Bibliográficos
Autores principales: Gregory, Brittany L., Cheung, Vivian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875861/
https://www.ncbi.nlm.nih.gov/pubmed/24285722
http://dx.doi.org/10.1101/gr.156141.113