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Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth
DNA sequence variants influence gene expression and cellular phenotypes. In this study, we focused on natural variation in the gene encoding the histone demethylase, KDM4C, which promotes transcriptional activation by removing the repressive histone mark, H3K9me3, from its target genes. We uncovered...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875861/ https://www.ncbi.nlm.nih.gov/pubmed/24285722 http://dx.doi.org/10.1101/gr.156141.113 |