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The significance of the alteration of 8-OHdG in serous ovarian carcinoma
BACKGROUND: Oxidative damage and DNA repair dysfunction are associated with carcinogenesis. 8-OHdG is one of the major oxidative DNA adducts. Present work aims to investigate whether the expression of 8-OHdG and its key repair gene hOGG1 play distinctive role in two types of serous ovarian cancer. M...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875897/ https://www.ncbi.nlm.nih.gov/pubmed/24165045 http://dx.doi.org/10.1186/1757-2215-6-74 |