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The significance of the alteration of 8-OHdG in serous ovarian carcinoma

BACKGROUND: Oxidative damage and DNA repair dysfunction are associated with carcinogenesis. 8-OHdG is one of the major oxidative DNA adducts. Present work aims to investigate whether the expression of 8-OHdG and its key repair gene hOGG1 play distinctive role in two types of serous ovarian cancer. M...

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Detalles Bibliográficos
Autores principales: Xu, Xia, Wang, Yan, Guo, Wenwen, Zhou, Yiqing, Lv, Chunmei, Chen, Xiaoxiang, Liu, Kaijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875897/
https://www.ncbi.nlm.nih.gov/pubmed/24165045
http://dx.doi.org/10.1186/1757-2215-6-74