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Vitamin D Is a Multilevel Repressor of Wnt/β-Catenin Signaling in Cancer Cells

The Wnt/β-catenin signaling pathway is abnormally activated in most colorectal cancers and in a proportion of other neoplasias. This activation initiates or contributes to carcinogenesis by regulating the expression of a large number of genes in tumor cells. The active vitamin D metabolite 1α,25-dih...

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Detalles Bibliográficos
Autores principales: Larriba, María Jesús, González-Sancho, José Manuel, Barbáchano, Antonio, Niell, Núria, Ferrer-Mayorga, Gemma, Muñoz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875938/
https://www.ncbi.nlm.nih.gov/pubmed/24202444
http://dx.doi.org/10.3390/cancers5041242