Cargando…

Vitamin D Is a Multilevel Repressor of Wnt/β-Catenin Signaling in Cancer Cells

The Wnt/β-catenin signaling pathway is abnormally activated in most colorectal cancers and in a proportion of other neoplasias. This activation initiates or contributes to carcinogenesis by regulating the expression of a large number of genes in tumor cells. The active vitamin D metabolite 1α,25-dih...

Descripción completa

Detalles Bibliográficos
Autores principales:	Larriba, María Jesús, González-Sancho, José Manuel, Barbáchano, Antonio, Niell, Núria, Ferrer-Mayorga, Gemma, Muñoz, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875938/ https://www.ncbi.nlm.nih.gov/pubmed/24202444 http://dx.doi.org/10.3390/cancers5041242

Ejemplares similares

The human PKP2/plakophilin‐2 gene is induced by Wnt/β‐catenin in normal and colon cancer‐associated fibroblasts
por: Niell, Núria, et al.
Publicado: (2017)

Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts
por: Ferrer-Mayorga, Gemma, et al.
Publicado: (2019)

Wnt and Vitamin D at the Crossroads in Solid Cancer
por: González-Sancho, José Manuel, et al.
Publicado: (2020)

Vitamin D Effects on Cell Differentiation and Stemness in Cancer
por: Fernández-Barral, Asunción, et al.
Publicado: (2020)

Vitamin D Receptor Deficiency Enhances Wnt/β-Catenin Signaling and Tumor Burden in Colon Cancer
por: Larriba, María Jesús, et al.
Publicado: (2011)

Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer
por: Ferrer-Mayorga, Gemma, et al.
Publicado: (2017)

Interaction of vitamin D with membrane-based signaling pathways
por: Larriba, María Jesús, et al.
Publicado: (2014)

Atractylochromene Is a Repressor of Wnt/β-Catenin Signaling in Colon Cancer Cells
por: Shim, Ah-Ram, et al.
Publicado: (2015)

Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/β-Catenin Signaling
por: Moreno-Marín, Nuria, et al.
Publicado: (2018)

RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells
por: Ordóñez-Morán, Paloma, et al.
Publicado: (2008)

Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin
por: Xu, Zhengshui, et al.
Publicado: (2021)

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling
por: Pálmer, Héctor G., et al.
Publicado: (2001)

Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids
por: Fernández‐Barral, Asunción, et al.
Publicado: (2019)

Organoids and Colorectal Cancer
por: Barbáchano, Antonio, et al.
Publicado: (2021)

miR-145 is differentially regulated by TGF-β(1) and ischaemia and targets Disabled-2 expression and wnt/β-catenin activity
por: Mayorga, Maritza E, et al.
Publicado: (2012)

Vitamin D and the Epithelial to Mesenchymal Transition
por: Larriba, María Jesús, et al.
Publicado: (2016)

WNKs in Wnt/β-catenin signaling
por: Serysheva, Ekatherina, et al.
Publicado: (2014)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling
por: Lin, Chung-Ming, et al.
Publicado: (2017)

Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
por: García-Martínez, José Manuel, et al.
Publicado: (2023)

Review: The Role of Wnt/β-Catenin Signalling in Neural Crest Development in Zebrafish
por: Sutton, Gemma, et al.
Publicado: (2021)

The Long Non-Coding HOTAIR Is Modulated by Cyclic Stretch and WNT/β-CATENIN in Human Aortic Valve Cells and Is a Novel Repressor of Calcification Genes
por: Carrion, Katrina, et al.
Publicado: (2014)

Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models
por: Song, Zhiqi, et al.
Publicado: (2017)

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins
por: Muñoz Bello, Jesus Omar, et al.
Publicado: (2015)

Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway
por: Jeong, Woo-Jeong, et al.
Publicado: (2018)

Wnt/β-catenin signaling in heart regeneration
por: Ozhan, Gunes, et al.
Publicado: (2015)

Wnt/β-catenin signaling and kidney fibrosis
por: Tan, Roderick J, et al.
Publicado: (2014)

Regulation of Wnt/β-catenin signaling by herpesviruses
por: Zwezdaryk, Kevin J, et al.
Publicado: (2016)

Wnt/β-catenin pathway in arrhythmogenic cardiomyopathy
por: Lorenzon, Alessandra, et al.
Publicado: (2017)

Wnt/β-Catenin Signaling in Liver Cancers
por: Wang, Wenhui, et al.
Publicado: (2019)

Wnt/β-Catenin Signaling in Oral Carcinogenesis
por: Reyes, Montserrat, et al.
Publicado: (2020)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling
por: Janda, Claudia Y., et al.
Publicado: (2017)

Running Against the Wnt: How Wnt/β-Catenin Suppresses Adipogenesis
por: de Winter, Twan J. J., et al.
Publicado: (2021)

Correction: The Long Non-Coding HOTAIR Is Modulated by Cyclic Stretch and WNT/β-CATENIN in Human Aortic Valve Cells and Is a Novel Repressor of Calcification Genes
Publicado: (2014)

Molecular Mechanism of Vitamin D Receptor Modulating Wnt/β-catenin Signaling Pathway in Gastric Cancer
por: Zhang, Ying, et al.
Publicado: (2023)

Snail1 transcriptional repressor binds to its own promoter and controls its expression
por: Peiró, Sandra, et al.
Publicado: (2006)

Activation of Intracellular Calcium by Multiple Wnt Ligands and Translocation of β-Catenin into the Nucleus: A CONVERGENT MODEL OF Wnt/Ca(2+) AND Wnt/β-CATENIN PATHWAYS
por: Thrasivoulou, Christopher, et al.
Publicado: (2013)

Novel β-carbolines inhibit Wnt/β-catenin signaling
por: Kong, L, et al.
Publicado: (2015)

Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target
por: Gerard, Brigitte, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_gn56jg166to7a2sbgtn56tkmgm