Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells

Diastereomeric and geometric analogs of calcipotriol, PRI-2202 and PRI-2205, were synthesized as advanced intermediates from vitamin D C-22 benzothiazoyl sulfones and side-chain aldehydes using our convergent strategy. Calcitriol, calcipotriol (PRI-2201) and tacalcitol (PRI-2191) were used as the re...

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Detalles Bibliográficos
Autores principales: Milczarek, Magdalena, Chodyński, Michał, Filip-Psurska, Beata, Martowicz, Agnieszka, Krupa, Małgorzata, Krajewski, Krzysztof, Kutner, Andrzej, Wietrzyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875943/
https://www.ncbi.nlm.nih.gov/pubmed/24202449
http://dx.doi.org/10.3390/cancers5041355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875943/
https://www.ncbi.nlm.nih.gov/pubmed/24202449
http://dx.doi.org/10.3390/cancers5041355

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