Investigation of siRNA Nanoparticle Formation Using Mono-Cationic Detergents and Its Use in Gene Silencing in Human HeLa Cells

The focus of recent research has been on the development of siRNA vectors to achieve an innovative gene therapy. Most of the conventional vectors are siRNA nanoparticles complexed with cationic polymers and liposomes, making it difficult to release siRNA. In this study, we report on the use of MCD,...

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Detalles Bibliográficos
Autores principales: Yamada, Yuma, Suzuki, Ryosuke, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875945/
https://www.ncbi.nlm.nih.gov/pubmed/24202451
http://dx.doi.org/10.3390/cancers5041413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875945/
https://www.ncbi.nlm.nih.gov/pubmed/24202451
http://dx.doi.org/10.3390/cancers5041413

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