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Autophagy variation within a cell population determines cell fate via selective degradation of Fap-1
Autophagy regulates cell death both positively and negatively, but the molecular basis for this paradox remains inadequately characterized. We demonstrate here that transient cell-to-cell variations in autophagy can either promote cell death or survival depending on the stimulus and cell type. By se...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876036/ https://www.ncbi.nlm.nih.gov/pubmed/24316673 http://dx.doi.org/10.1038/ncb2886 |