Smad3 Deficiency Ameliorates Hepatic Fibrogenesis through the Expression of Senescence Marker Protein-30, an Antioxidant-Related Protein

Smad3 is a key mediator of the transforming growth factor (TGF)-β1 signaling pathway that plays central role in inflammation and fibrosis. In present study, we evaluated the effect of Smad3 deficiency in Smad3(−/−) mice with carbon tetrachloride (CCl(4))-induced liver fibrosis. The animals were rece...

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Detalles Bibliográficos
Autores principales: Jeong, Da-Hee, Hwang, Meeyul, Park, Jin-Kyu, Goo, Moon-Jung, Hong, Il-Hwa, Ki, Mi-Ran, Ishigami, Akihito, Kim, Ah-Young, Lee, Eun-Mi, Lee, Eun-Joo, Jeong, Kyu-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876072/
https://www.ncbi.nlm.nih.gov/pubmed/24304543
http://dx.doi.org/10.3390/ijms141223700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876072/
https://www.ncbi.nlm.nih.gov/pubmed/24304543
http://dx.doi.org/10.3390/ijms141223700

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