Tandem Aldol-Michael Reactions in Aqueous Diethylamine Medium: A Greener and Efficient Approach to Bis-Pyrimidine Derivatives

A simple protocol, involving the green synthesis for the construction of novel bis-pyrimidine derivatives, 3a–i and 4a–e are accomplished by the aqueous diethylamine media promoted tandem Aldol-Michael reaction between two molecules of barbituric acid derivatives 1a,b with various aldehydes. This ef...

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Detalles Bibliográficos
Autores principales: Al-Majid, Abdullah M., Barakat, Assem, AL-Najjar, Hany J., Mabkhot, Yahia N., Ghabbour, Hazem A., Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876076/
https://www.ncbi.nlm.nih.gov/pubmed/24317435
http://dx.doi.org/10.3390/ijms141223762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876076/
https://www.ncbi.nlm.nih.gov/pubmed/24317435
http://dx.doi.org/10.3390/ijms141223762

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