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The Dual Role of Smad7 in the Control of Cancer Growth and Metastasis

Smad7 was initially identified as an inhibitor of Transforming growth factor (TGF)-β due mainly to its ability to bind TGF-β receptor type I and prevent TGF-β-associated Smad signaling. More recently, it has been demonstrated that Smad7 can interact with other intracellular proteins and regulate als...

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Detalles Bibliográficos
Autores principales: Stolfi, Carmine, Marafini, Irene, De Simone, Veronica, Pallone, Francesco, Monteleone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876077/
https://www.ncbi.nlm.nih.gov/pubmed/24317436
http://dx.doi.org/10.3390/ijms141223774