Alteration of Dynein Function Affects α-Synuclein Degradation via the Autophagosome-Lysosome Pathway

Growing evidence suggests that dynein dysfunction may be implicated in the pathogenesis of neurodegeneration. It plays a central role in aggresome formation, the delivery of autophagosome to lysosome for fusion and degradation, which is a pro-survival mechanism essential for the bulk degradation of...

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Detalles Bibliográficos
Autores principales: Li, Da, Shi, Ji-Jun, Mao, Cheng-Jie, Liu, Sha, Wang, Jian-Da, Chen, Jing, Wang, Fen, Yang, Ya-Ping, Hu, Wei-Dong, Hu, Li-Fang, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876108/
https://www.ncbi.nlm.nih.gov/pubmed/24351814
http://dx.doi.org/10.3390/ijms141224242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876108/
https://www.ncbi.nlm.nih.gov/pubmed/24351814
http://dx.doi.org/10.3390/ijms141224242

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