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Genomic and computational approaches to dissect the mechanisms of STAT3’s universal and cell type-specific functions

STAT3 is the quintessential pleiotropic transcription factor with many biological roles throughout development as well as in multiple adult tissues. Its functional heterogeneity is encoded in the range of genome-wide binding patterns that specify different regulatory networks in distinct cell types....

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Detalles Bibliográficos
Autores principales: Hutchins, Andrew Paul, Diez, Diego, Miranda-Saavedra, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876425/
https://www.ncbi.nlm.nih.gov/pubmed/24416643
http://dx.doi.org/10.4161/jkst.25097