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Redox regulation of Janus kinase: The elephant in the room

The redox regulation of Janus kinases (JAKs) is a complex subject. Due to other redox-sensitive kinases in the kinome, redox-sensitive phosphatases, and cellular antioxidant systems and reactive oxygen species (ROS) production systems, the net biological outcomes of oxidative stress on JAK-dependent...

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Detalles Bibliográficos
Autor principal: Duhé, Roy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876428/
https://www.ncbi.nlm.nih.gov/pubmed/24416654
http://dx.doi.org/10.4161/jkst.26141