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The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies
Telomerase, comprising a reverse transcriptase protein (TERT) and an RNA template, plays a critical role during senescence and carcinogenesis; however, the mechanisms by which telomerase is regulated remain to be elucidated. Several signaling pathways are involved in the activation of TERT at multis...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876434/ https://www.ncbi.nlm.nih.gov/pubmed/24416646 http://dx.doi.org/10.4161/jkst.25256 |