STAT2 phosphorylation and signaling

STAT2 is an essential transcription factor in type I IFN mediated anti-viral and anti-proliferative signaling. STAT2 function is regulated by tyrosine phosphorylation, which is the trigger for STAT-dimerization, subsequent nuclear translocation, and transcriptional activation of IFN stimulated genes...

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Detalles Bibliográficos
Autores principales: Steen, Håkan C, Gamero, Ana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876438/
https://www.ncbi.nlm.nih.gov/pubmed/24416652
http://dx.doi.org/10.4161/jkst.25790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876438/
https://www.ncbi.nlm.nih.gov/pubmed/24416652
http://dx.doi.org/10.4161/jkst.25790

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