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STAT2 phosphorylation and signaling

STAT2 is an essential transcription factor in type I IFN mediated anti-viral and anti-proliferative signaling. STAT2 function is regulated by tyrosine phosphorylation, which is the trigger for STAT-dimerization, subsequent nuclear translocation, and transcriptional activation of IFN stimulated genes...

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Detalles Bibliográficos
Autores principales:	Steen, Håkan C, Gamero, Ana M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876438/ https://www.ncbi.nlm.nih.gov/pubmed/24416652 http://dx.doi.org/10.4161/jkst.25790

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