Cargando…

Crizotinib: A comprehensive review

Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahu, Arvind, Prabhash, Kumar, Noronha, Vanita, Joshi, Amit, Desai, Saral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876666/
https://www.ncbi.nlm.nih.gov/pubmed/24455567
http://dx.doi.org/10.4103/2278-330X.110506