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Error Analysis of Deep Sequencing of Phage Libraries: Peptides Censored in Sequencing

Next-generation sequencing techniques empower selection of ligands from phage-display libraries because they can detect low abundant clones and quantify changes in the copy numbers of clones without excessive selection rounds. Identification of errors in deep sequencing data is the most critical ste...

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Detalles Bibliográficos
Autores principales: Matochko, Wadim L., Derda, Ratmir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876701/
https://www.ncbi.nlm.nih.gov/pubmed/24416071
http://dx.doi.org/10.1155/2013/491612