Structure of the FMNL3 FH2/actin complex provides insight into formin-mediated actin nucleation and elongation

Formins are actin assembly factors that act in a variety of actin-based processes. The conserved formin homology 2 (FH2) domain promotes filament nucleation and influences elongation via interaction with the barbed end. FMNL3 is a formin that induces assembly of filopodia but whose FH2 domain is a p...

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Detalles Bibliográficos
Autores principales: Thompson, Morgan E., Heimsath, Ernest G., Gauvin, Timothy J., Higgs, Henry N., Kull, F. Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876896/
https://www.ncbi.nlm.nih.gov/pubmed/23222643
http://dx.doi.org/10.1038/nsmb.2462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876896/
https://www.ncbi.nlm.nih.gov/pubmed/23222643
http://dx.doi.org/10.1038/nsmb.2462

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