Cargando…
Structure of the FMNL3 FH2/actin complex provides insight into formin-mediated actin nucleation and elongation
Formins are actin assembly factors that act in a variety of actin-based processes. The conserved formin homology 2 (FH2) domain promotes filament nucleation and influences elongation via interaction with the barbed end. FMNL3 is a formin that induces assembly of filopodia but whose FH2 domain is a p...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876896/ https://www.ncbi.nlm.nih.gov/pubmed/23222643 http://dx.doi.org/10.1038/nsmb.2462 |