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Proteomic Profiling of Exosomes Leads to the Identification of Novel Biomarkers for Prostate Cancer

BACKGROUND: Current markers for prostate cancer, such as PSA lack specificity. Therefore, novel biomarkers are needed. Unfortunately, the complexity of body fluids often hampers biomarker discovery. An attractive alternative approach is the isolation of small vesicles, i.e. exosomes, ∼100 nm, which...

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Detalles Bibliográficos
Autores principales: Duijvesz, Diederick, Burnum-Johnson, Kristin E., Gritsenko, Marina A., Hoogland, A. Marije, Vredenbregt-van den Berg, Mirella S., Willemsen, Rob, Luider, Theo, Paša-Tolić, Ljiljana, Jenster, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876995/
https://www.ncbi.nlm.nih.gov/pubmed/24391718
http://dx.doi.org/10.1371/journal.pone.0082589