Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy

In order to realise the full potential of cancer suicide gene therapy that allows the precise expression of suicide gene in cancer cells, we used a tissue specific Epithelial cell adhesion molecule (EpCAM) promoter (EGP-2) that directs transgene Herpes simplex virus–thymidine kinase (HSV-TK) express...

Descripción completa

Detalles Bibliográficos
Autores principales: Danda, Ravikanth, Krishnan, Gopinath, Ganapathy, Kalaivani, Krishnan, Uma Maheswari, Vikas, Khetan, Elchuri, Sailaja, Chatterjee, Nivedita, Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877029/
https://www.ncbi.nlm.nih.gov/pubmed/24391761
http://dx.doi.org/10.1371/journal.pone.0083398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877029/
https://www.ncbi.nlm.nih.gov/pubmed/24391761
http://dx.doi.org/10.1371/journal.pone.0083398

Ejemplares similares