Cargando…

Substantial Conformational Change Mediated by Charge-Triad Residues of the Death Effector Domain in Protein-Protein Interactions

Protein conformational changes are commonly associated with the formation of protein complexes. The non-catalytic death effector domains (DEDs) mediate protein-protein interactions in a variety of cellular processes, including apoptosis, proliferation and migration, and glucose metabolism. Here, usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Twomey, Edward C., Cordasco, Dana F., Kozuch, Stephen D., Wei, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877032/
https://www.ncbi.nlm.nih.gov/pubmed/24391764
http://dx.doi.org/10.1371/journal.pone.0083421