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Substantial Conformational Change Mediated by Charge-Triad Residues of the Death Effector Domain in Protein-Protein Interactions
Protein conformational changes are commonly associated with the formation of protein complexes. The non-catalytic death effector domains (DEDs) mediate protein-protein interactions in a variety of cellular processes, including apoptosis, proliferation and migration, and glucose metabolism. Here, usi...
Autores principales: | Twomey, Edward C., Cordasco, Dana F., Kozuch, Stephen D., Wei, Yufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877032/ https://www.ncbi.nlm.nih.gov/pubmed/24391764 http://dx.doi.org/10.1371/journal.pone.0083421 |
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