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Concomitant Interferon Alpha Stimulation and TLR3 Activation Induces Neuronal Expression of Depression-Related Genes That Are Elevated in the Brain of Suicidal Persons

We have previously identified 15 genes that are associated with the development of severe depressive side effects during the standard therapy with interferon alpha and ribavirin in the peripheral blood of hepatitis C virus infected patients. An enhanced expression of these genes was also found in th...

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Detalles Bibliográficos
Autores principales: Hoyo-Becerra, Carolina, Huebener, Anastasia, Trippler, Martin, Lutterbeck, Melanie, Liu, Zijian J., Truebner, Kurt, Bajanowski, Thomas, Gerken, Guido, Hermann, Dirk M., Schlaak, Joerg F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877033/
https://www.ncbi.nlm.nih.gov/pubmed/24391741
http://dx.doi.org/10.1371/journal.pone.0083149