Evodiamine Inhibits Insulin-Stimulated mTOR-S6K Activation and IRS1 Serine Phosphorylation in Adipocytes and Improves Glucose Tolerance in Obese/Diabetic Mice

Evodiamine, an alkaloid extracted from the dried unripe fruit of the tree Evodia rutaecarpa Bentham (Rutaceae), reduces obesity and insulin resistance in obese/diabetic mice; however, the mechanism underlying the effect of evodiamine on insulin resistance is unknown. This study investigated the effe...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Kusudo, Tatsuya, Takeuchi, Tamaki, Yamashita, Yukari, Kontani, Yasuhide, Okamatsu, Yuko, Saito, Masayuki, Mori, Nozomu, Yamashita, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877036/
https://www.ncbi.nlm.nih.gov/pubmed/24391749
http://dx.doi.org/10.1371/journal.pone.0083264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877036/
https://www.ncbi.nlm.nih.gov/pubmed/24391749
http://dx.doi.org/10.1371/journal.pone.0083264

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