Kinetic and Structural Studies of Aldehyde Oxidoreductase from Desulfovibrio gigas Reveal a Dithiolene-Based Chemistry for Enzyme Activation and Inhibition by H(2)O(2)

Mononuclear Mo-containing enzymes of the xanthine oxidase (XO) family catalyze the oxidative hydroxylation of aldehydes and heterocyclic compounds. The molybdenum active site shows a distorted square-pyramidal geometry in which two ligands, a hydroxyl/water molecule (the catalytic labile site) and a...

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Detalles Bibliográficos
Autores principales: Marangon, Jacopo, Correia, Hugo D., Brondino, Carlos D., Moura, José J. G., Romão, Maria J., González, Pablo J., Santos-Silva, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877041/
https://www.ncbi.nlm.nih.gov/pubmed/24391748
http://dx.doi.org/10.1371/journal.pone.0083234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877041/
https://www.ncbi.nlm.nih.gov/pubmed/24391748
http://dx.doi.org/10.1371/journal.pone.0083234

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