Redox Specificity of 2-Hydroxyacid-Coupled NAD(+)/NADH Dehydrogenases: A Study Exploiting “Reactive” Arginine as a Reporter of Protein Electrostatics

With “reactive” arginine as a kinetic reporter, 2-hydroxyacid dehydrogenases are assessed in basis of their specialization as NAD(+)-reducing or NADH-oxidizing enzymes. Specifically, M4 and H4 lactate dehydrogenases (LDHs) and cytoplasmic and mitochondrial malate dehydrogenases (MDHs) are compared t...

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Detalles Bibliográficos
Autores principales: Gupta, Pooja, Jairajpuri, Mohamad Aman, Durani, Susheel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877072/
https://www.ncbi.nlm.nih.gov/pubmed/24391777
http://dx.doi.org/10.1371/journal.pone.0083505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877072/
https://www.ncbi.nlm.nih.gov/pubmed/24391777
http://dx.doi.org/10.1371/journal.pone.0083505

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