Metformin as an Adjuvant Drug against Pediatric Sarcomas: Hypoxia Limits Therapeutic Effects of the Drug

Metformin, a well-known insulin-sensitizer commonly used for type 2 diabetes therapy, has recently emerged as potentially very attractive drug also in oncology. It is cheap, it is relatively safe and many reports have indicated effects in cancer prevention and therapy. These desirable features are p...

Descripción completa

Detalles Bibliográficos
Autores principales: Garofalo, Cecilia, Capristo, Mariantonietta, Manara, Maria Cristina, Mancarella, Caterina, Landuzzi, Lorena, Belfiore, Antonino, Lollini, Pier-Luigi, Picci, Piero, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877110/
https://www.ncbi.nlm.nih.gov/pubmed/24391834
http://dx.doi.org/10.1371/journal.pone.0083832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877110/
https://www.ncbi.nlm.nih.gov/pubmed/24391834
http://dx.doi.org/10.1371/journal.pone.0083832

Ejemplares similares