Cargando…
Metformin as an Adjuvant Drug against Pediatric Sarcomas: Hypoxia Limits Therapeutic Effects of the Drug
Metformin, a well-known insulin-sensitizer commonly used for type 2 diabetes therapy, has recently emerged as potentially very attractive drug also in oncology. It is cheap, it is relatively safe and many reports have indicated effects in cancer prevention and therapy. These desirable features are p...
Autores principales: | Garofalo, Cecilia, Capristo, Mariantonietta, Manara, Maria Cristina, Mancarella, Caterina, Landuzzi, Lorena, Belfiore, Antonino, Lollini, Pier-Luigi, Picci, Piero, Scotlandi, Katia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877110/ https://www.ncbi.nlm.nih.gov/pubmed/24391834 http://dx.doi.org/10.1371/journal.pone.0083832 |
Ejemplares similares
-
Preclinical Effectiveness of Selective Inhibitor of IRS-1/2 NT157 in Osteosarcoma Cell Lines
por: Garofalo, Cecilia, et al.
Publicado: (2015) -
Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma
por: Landuzzi, Lorena, et al.
Publicado: (2023) -
An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas
por: Guerzoni, Clara, et al.
Publicado: (2014) -
Targeting Glutathione-S Transferase Enzymes in Musculoskeletal Sarcomas: A Promising Therapeutic Strategy
por: Pasello, Michela, et al.
Publicado: (2011) -
Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma
por: Landuzzi, Lorena, et al.
Publicado: (2021)