An Analysis of Interactions between Fluorescently-Tagged Mutant and Wild-Type SOD1 in Intracellular Inclusions

BACKGROUND: By mechanisms yet to be discerned, the co-expression of high levels of wild-type human superoxide dismutase 1 (hSOD1) with variants of hSOD1 encoding mutations linked familial amyotrophic lateral sclerosis (fALS) hastens the onset of motor neuron degeneration in transgenic mice. Although...

Descripción completa

Detalles Bibliográficos
Autores principales: Qualls, David A., Crosby, Keith, Brown, Hilda, Borchelt, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877123/
https://www.ncbi.nlm.nih.gov/pubmed/24391857
http://dx.doi.org/10.1371/journal.pone.0083981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877123/
https://www.ncbi.nlm.nih.gov/pubmed/24391857
http://dx.doi.org/10.1371/journal.pone.0083981

Ejemplares similares