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Riociguat Reduces Infarct Size and Post-Infarct Heart Failure in Mouse Hearts: Insights from MRI/PET Imaging

AIM: Stimulation of the nitric oxide (NO) – soluble guanylate (sGC) - protein kinase G (PKG) pathway confers protection against acute ischaemia/reperfusion injury, but more chronic effects in reducing post-myocardial infarction (MI) heart failure are less defined. The aim of this study was to not on...

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Detalles Bibliográficos
Autores principales: Methner, Carmen, Buonincontri, Guido, Hu, Chou-Hui, Vujic, Ana, Kretschmer, Axel, Sawiak, Stephen, Carpenter, Adrian, Stasch, Johannes-Peter, Krieg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877128/
https://www.ncbi.nlm.nih.gov/pubmed/24391843
http://dx.doi.org/10.1371/journal.pone.0083910