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CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer's Disease

BACKGROUND: CHRNA7 encodes the α7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission. Previously, CHRNA7 polymorphisms have not been related to cholinesterase inhibitors (ChEI) response. METHODS: Mild to modera...

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Detalles Bibliográficos
Autores principales: Weng, Pei-Hsuan, Chen, Jen-Hau, Chen, Ta-Fu, Sun, Yu, Wen, Li-Li, Yip, Ping-Keung, Chu, Yi-Min, Chen, Yen-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877150/
https://www.ncbi.nlm.nih.gov/pubmed/24391883
http://dx.doi.org/10.1371/journal.pone.0084059