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HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

An effective HIV vaccine will most likely require the induction of strong T-cell responses, broadly neutralizing antibodies (bNAbs), and the elicitation of antibody-dependent cellular cytotoxicity (ADCC). Previously, we demonstrated the induction of strong HIV/SIV cellular immune responses in macaqu...

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Detalles Bibliográficos
Autores principales: Muthumani, Kar, Wise, Megan C., Broderick, Kate E., Hutnick, Natalie, Goodman, Jonathan, Flingai, Seleeke, Yan, Jian, Bian, Chaoran B., Mendoza, Janess, Tingey, Colleen, Wilson, Christine, Wojtak, Krzysztof, Sardesai, Niranjan Y., Weiner, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877240/
https://www.ncbi.nlm.nih.gov/pubmed/24391921
http://dx.doi.org/10.1371/journal.pone.0084234