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The Wnt Serpentine Receptor Frizzled-9 Regulates New Bone Formation in Fracture Healing

Wnt signaling is a key regulator of bone metabolism and fracture healing. The canonical Wnt/β-catenin pathway is regarded as the dominant mechanism, and targeting this pathway has emerged as a promising strategy for the treatment of osteoporosis and poorly healing fractures. In contrast, little is k...

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Detalles Bibliográficos
Autores principales: Heilmann, Aline, Schinke, Thorsten, Bindl, Ronny, Wehner, Tim, Rapp, Anna, Haffner-Luntzer, Melanie, Nemitz, Claudia, Liedert, Astrid, Amling, Michael, Ignatius, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877253/
https://www.ncbi.nlm.nih.gov/pubmed/24391920
http://dx.doi.org/10.1371/journal.pone.0084232