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Xenograft Tumors Vascularized with Murine Blood Vessels May Overestimate the Effect of Anti-Tumor Drugs: A Pilot Study

Recent evidence demonstrated that endothelial cells initiate signaling events that enhance tumor cell survival, proliferation, invasion, and tumor recurrence. Under this new paradigm for cellular crosstalk within the tumor microenvironment, the origin of endothelial cells and tumor cells may have a...

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Detalles Bibliográficos
Autores principales: Dong, Zhihong, Imai, Atsushi, Krishnamurthy, Sudha, Zhang, Zhaocheng, Zeitlin, Benjamin D., Nör, Jacques E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877272/
https://www.ncbi.nlm.nih.gov/pubmed/24391922
http://dx.doi.org/10.1371/journal.pone.0084236