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Xenograft Tumors Vascularized with Murine Blood Vessels May Overestimate the Effect of Anti-Tumor Drugs: A Pilot Study
Recent evidence demonstrated that endothelial cells initiate signaling events that enhance tumor cell survival, proliferation, invasion, and tumor recurrence. Under this new paradigm for cellular crosstalk within the tumor microenvironment, the origin of endothelial cells and tumor cells may have a...
Autores principales: | Dong, Zhihong, Imai, Atsushi, Krishnamurthy, Sudha, Zhang, Zhaocheng, Zeitlin, Benjamin D., Nör, Jacques E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877272/ https://www.ncbi.nlm.nih.gov/pubmed/24391922 http://dx.doi.org/10.1371/journal.pone.0084236 |
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