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Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling

The dopamine D2 receptor (DRD2) is a key receptor that mediates dopamine-associated brain functions such as mood, reward, and emotion. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase whose function has been implicated in the brain reward circuit. In this study, we reve...

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Detalles Bibliográficos
Autores principales: Jeong, Jaehoon, Park, Young-Un, Kim, Dae-Kyum, Lee, Saebom, Kwak, Yongdo, Lee, Seol-Ae, Lee, Haeryun, Suh, Yoo-Hun, Gho, Yong Song, Hwang, Daehee, Park, Sang Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877277/
https://www.ncbi.nlm.nih.gov/pubmed/24391960
http://dx.doi.org/10.1371/journal.pone.0084482