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A New Strategy for Enhancing the Oral Bioavailability of Drugs with Poor Water-Solubility and Low Liposolubility Based on Phospholipid Complex and Supersaturated SEDDS

A novel supersaturated self-emulsifying drug delivery system (Super-SEDDS) loaded with scutellarin-phospholipid complex (SPC) was developed. The system aimed to address the limitations presented by conventional SEDDS as delivery carriers for drugs with poor water-solubility, low liposolubility and h...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Wan, Jiangling, Wu, Lei, Yi, Tao, Liu, Wei, Xu, Huibi, Yang, Xiangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877285/
https://www.ncbi.nlm.nih.gov/pubmed/24391965
http://dx.doi.org/10.1371/journal.pone.0084530