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A New Strategy for Enhancing the Oral Bioavailability of Drugs with Poor Water-Solubility and Low Liposolubility Based on Phospholipid Complex and Supersaturated SEDDS
A novel supersaturated self-emulsifying drug delivery system (Super-SEDDS) loaded with scutellarin-phospholipid complex (SPC) was developed. The system aimed to address the limitations presented by conventional SEDDS as delivery carriers for drugs with poor water-solubility, low liposolubility and h...
Autores principales: | Zhou, Hui, Wan, Jiangling, Wu, Lei, Yi, Tao, Liu, Wei, Xu, Huibi, Yang, Xiangliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877285/ https://www.ncbi.nlm.nih.gov/pubmed/24391965 http://dx.doi.org/10.1371/journal.pone.0084530 |
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