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Analysis of RXR/THR and RXR/PPARG2 Heterodimerization by Bioluminescence Resonance Energy Transfer (BRET)

BACKGROUND: Nuclear receptors (NR) regulate transcription of genes involved in many biological processes such as development, cell proliferation, differentiation and cell death. Amongst them, PPARG2 and THR control tissue glucose and lipid homeostasis which are deregulated in severe pathophysiologic...

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Detalles Bibliográficos
Autores principales: Mulero, Miquel, Perroy, Julie, Federici, Carole, Cabello, Gérard, Ollendorff, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877338/
https://www.ncbi.nlm.nih.gov/pubmed/24391967
http://dx.doi.org/10.1371/journal.pone.0084569