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A More Desirable Balanced Polyunsaturated Fatty Acid Composition Achieved by Heterologous Expression of Δ15/Δ4 Desaturases in Mammalian Cells

Arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are the most biologically active polyunsaturated fatty acids, but their biosyntheses in mammals are very limited. The biosynthesis of DHA is the most difficult, because this undergoes the Sprecher pathway–a further elongation...

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Detalles Bibliográficos
Autores principales: Zhu, Guiming, Ou, Qin, Zhang, Tao, Jiang, Xudong, Sun, Guozhi, Zhang, Ning, Wang, Kunfu, Fang, Heng, Wang, Mingfu, Sun, Jie, Ge, Tangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877351/
https://www.ncbi.nlm.nih.gov/pubmed/24391980
http://dx.doi.org/10.1371/journal.pone.0084871